The effect of Crocus sativus L. (saffron) herbal tea on happiness in postmenopausal women: a randomized controlled trial.

BMC complementary medicine and therapies. 2023;23(1):176
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Menopause is one of the natural processes in a female’s life, the most prominent feature of which is the end of fertility and menstruation. Following the psychosocial changes in this period of life, there is considerable evidence that reproductive hormones, especially oestrogen, may influence mood. The aim of this study was to determine the effect of saffron tea on the postmenopausal women’s happiness This study was a randomised controlled trial which enrolled postmenopausal women. Participants (n=72) were randomly assigned to the intervention or control group. The intervention was the use of 30 mg dried stigmas of the saffron plant which was boiled once; one cup of saffron tea was consumed daily with white rock candy. Whereas the control group consumed lukewarm water and white rock candy. Results show that saffron herbal tea significantly increased the mean score of happiness in postmenopausal women, and there was a statistically significant difference between the intervention and control groups. Authors conclude that people should consult with their doctor, and in case he/she approves, use complementary therapies such as saffron herbal teas along with other drugs prescribed by the doctor.

Abstract

BACKGROUND Evidence suggests that menopause can be associated with a variety of negative psychological changes such as depression and anxiety, and improving the mental health status of women during menopause is one of the important priorities and challenges of the health system. The aim of this study was to determine the effect of saffron (Crocus sativus L., Iridaceae) herbal tea on happiness in postmenopausal women. METHODS In this randomized clinical trial which was conducted in 2021, 72 postmenopausal women were enrolled and divided into intervention and control groups. The randomization blocks method was used for random allocation, and the Oxford Happiness Questionnaire was utilized to measure the scores. The intervention included the use of 30 mg of dried stigmas of the saffron plant, which was boiled once (in the morning, in 300 ml of boiling water for 10-15 min) and consumed with white rock candy as one cup of saffron tea daily. To compare the trend of changes and after removing the effect of other variables, generalized estimating equation (GEE) was used. RESULTS There was no significant difference between the intervention and control groups in any of the quantitative and qualitative characteristics (p > 0.05). The results of paired samples t-test showed that the happiness mean score in the intervention group increased significantly (p < 0.001) from 42.93 ± 8.54 to 61.58 ± 8.24, while in the control group, there was no significant difference between the happiness mean score at the beginning and end of the study (p = 0.861). Also, after applying the treatment program in the intervention group, there was a significant difference between the two groups in terms of the happiness mean scores (p < 0.001). CONCLUSION Saffron herbal tea had a positive effect on reducing depression and increasing the happiness score; thus, it is recommended that it should be used as a complementary treatment in consultation with the treating physician. TRIAL REGISTRATION The present study was registered with the code of IRCT20210403050818N1 (Registration date: 09/04/2021) in the Iranian Registry of Clinical Trials. It was also approved by the Ethics Committee of Larestan University of Medical Sciences (Approval ID: IR.LARUMS.REC.1399.017).

Lifestyle medicine

Fundamental Clinical Imbalances : Hormonal ; Neurological
Patient Centred Factors : Triggers/Saffron herbal tea
Environmental Inputs : Diet ; Nutrients
Personal Lifestyle Factors : Nutrition
Functional Laboratory Testing : Not applicable

Methodological quality

Jadad score : 3
Allocation concealment : Yes

Metadata

Nutrition Evidence keywords : Menopause ; Saffron ; Herbal tea ; Oestrogen ; Hormones